The final event of the PGA Tour season is upon us, and every golfer will be trying to add to his FedEx Cup points total this week at the 2022 Wyndham Championship. The top 125 golfers after this week’s tournament at Sedgefield Country Club in Greensboro, N.C. advance to next week’s St. Jude Championship. Webb Simpson and Rickie Fowler were among those who cracked the playoff tier when the suspended golfers from LIV were removed from the list, with Simpson moving to 117th and Fowler to 123rd. Cameron Champ (130th) wasn’t so lucky, and Austin Smotherman is the man straddling the bubble at 125th. Will Zalatoris, Shane Lowry and Billy Horschel are among the headliners of this week’s field and will be looking to pad their point totals for what they hope will be a run to the Tour Championship in three weeks.

Zalatoris (16-1), Lowry (16-1) and Sungjae Im (16-1) are the co-favorites in the latest 2022 Wyndham Championship odds from Caesars Sportsbook. Simpson (18-1) and Horschel (20-1) are right behind, followed by Russell Henley (22-1) and 2016 Wyndham champ Si Woo Kim (28-1). Kevin Kisner, who won in a six-man playoff last year that also included Kim, is priced at 55-1. Champ (65-1), Fowler (125-1) and Smotherman (150-1) also are longshots in the Wyndham Championship 2022 field. Before making any 2022 Wyndham Championship picks, you need to see the PGA predictions and best bets from SportsLine golf insider Patrick McDonald.

After spending time at FanSided and NBC Sports EDGE, McDonald joined CBS Sports as a golf writer in the spring of 2022. Now covering the sport from a broader perspective, McDonald still likes to dip his toes into the betting pools on a weekly basis on the PGA Tour.

He takes a measured approach to his outright selections and is up more than 52 units on those plays in 2022, having hit Cameron Smith (22-1) at the Tournament of Champions, Hudson Swafford (250-1) at The American Express, Joaquin Niemann (70-1) at the Genesis Invitational and Justin Thomas (66-1) live at the PGA Championship.

McDonald just missed on his long-shot play at last week’s Rocket Mortgage Classic, with 80-1 shot Taylor Pendrith battling for the lead all week until winner Tony Finau’s dominant Sunday. The expert also pegged Pendrith as the first-round leader at 70-1, and the Canadian shared that honor with Finau after both shot 64 on Thursday. Pendrith ended up tied for second alongside reigning FedEx Cup champion Patrick Cantlay .

At the 3M Open the previous week, McDonald nailed both of his prop plays, taking Cam Davis as the top Australian finisher (+140) and Sahith Theegala to miss the cut (+275). The expert is up more than eight units on his PGA Tour props.

Now, McDonald has studied the 2022 Wyndham Championship field and is locking in his best bets, top sleepers and favorites to avoid. You can head to SportsLine now to see all of his 2022 Wyndham Championship picks and predictions.

Top 2022 Wyndham Championship expert picks

One stunning prediction from McDonald: Simpson’s success at Sedgefield won’t continue this year. The expert is fading the 2011 Wyndham winner, who has finished in the top 10 in nine of 13 appearances. He tied for seventh (behind the six playoff participants) last year and was in the top three the previous four years. But the 36-year-old was T-69 last week and has one top-10 finish since last year’s Wyndham. That was in November, so he is unlikely to contend this week.      

On the other hand, Tyrrell Hatton hasn’t been in contention much but is one of the best players in the field and the expert is backing him this week. The last time we saw Hatton, he tied for 11th at the Open Championship at St. Andrews, and that was with an uncharacteristically unreliable putter. The Englishman is fifth on tour in strokes gained putting, so that should come back. He hit almost 81 percent of his greens in regulation at The Open, his best performance of the year. See who else to pick here.

How to make 2022 Wyndham Championship golf picks

McDonald’s best bets for the 2022 Wyndham Championship include a massive triple-digit long shot. This golfer has had some injury issues but has a high ceiling and is still showing a great short game. He could pull off a stunning result this week. Find out who it is, and see the rest of McDonald’s picks, over at SportsLine.

So what 2022 Wyndham Championship picks should you target? And which massive long shot should you back at the Wyndham Championship 2022? Check out the odds below, then visit SportsLine to see Patrick McDonald’s top picks for Wyndham Championship 2022, all from the expert who’s up more than 52 units on outright plays in 2022.

2022 Wyndham Championship odds, field, top contenders

See full Wyndham Championship 2022 picks, best bets, and predictions here. 

Will Zalatoris 16-1
Shane Lowry 16-1
Webb Simpson 18-1
Billy Horschel 20-1
Sungjae Im 20-1
Corey Conners 25-1
Russell Henley 28-1
Adam Scott 30-1
Taylor Pendrith 30-1
Justin Rose 35-1
Joohyung Kim 35-1
Denny McCarthy 35-1
Davis Riley 35-1
Tyrrell Hatton 35-1
Si Woo Kim 35-1
Harold Varner III 35-1
Aaron Wise 40-1
Keith Mitchell 40-1
Kevin Kisner 40-1
Brian Harman 45-1
Sebastian Munoz 45-1
Christiaan Bezuidenhout 45-1
Jason Day 45-1
J.T. Poston 50-1
Jhonattan Vegas 60-1
Kevin Streelman 60-1
Adam Long 70-1
Scott Stallings 70-1
Cameron Champ 70-1
Chris Gotterup 70-1
Mark Hubbard 75-1
Alex Smalley 75-1
Lee Hodges 75-1
Nick Hardy 80-1
C.T. Pan 80-1
Joel Dahmen 80-1
Brendon Todd 80-1
Anirban Lahiri 90-1
Martin Laird 90-1
J.J. Spaun 90-1
Stewart Cink 90-1
Rickie Fowler 100-1
Aaron Rai 100-1
Greyson Sigg 100-1
Doug Ghim 100-1
Callum Tarren 100-1
Stephan Jaeger 100-1
Adam Svensson 100-1
K.H. Lee 100-1
Adam Schenk 100-1
Patrick Rodgers 100-1
Harris English 100-1
Ryan Armour 100-1
Taylor Moore 100-1
Matthew NeSmith 125-1
Andrew Putnam 125-1
Vince Whaley 125-1
Russell Knox 125-1
Mackenzie Hughes 125-1
Hank Lebioda 125-1
Patton Kizzire 125-1
Austin Smotherman 125-1
Danny Willett 125-1
Sepp Straka 125-1
Peter Malnati 125-1
Tyler Duncan 125-1
Chad Ramey 125-1
David Lipsky 150-1
Matthias Schwab 150-1
James Hahn 150-1
Danny Lee 150-1
Chez Reavie 150-1
Rory Sabbatini 150-1
Chesson Hadley 150-1
Matt Wallace 150-1
Lucas Glover 150-1
John Huh 150-1
Sam Ryder 175-1
Brice Garnett 175-1
Vaughn Taylor 175-1
Michael Gligic 175-1
Joseph Bramlett 175-1
Scott Piercy 175-1
Cameron Percy 175-1
Hayden Buckley 175-1
Charley Hoffman 175-1
Brandon Wu 175-1
Michael Thompson 200-1
Doc Redman 225-1
Nick Taylor 225-1
Andrew Novak 225-1
Kramer Hickok 225-1
Justin Lower 225-1
Chase Seiffert 250-1
Seung-Yul Noh 250-1
Ryan Moore 250-1
Zach Johnson 275-1
Kelly Kraft 275-1
Ben Martin 275-1
Satoshi Kodaira 275-1
Robert Streb 300-1
Scott Brown 300-1
Ben Griffin 300-1
Kevin Chappell 300-1
Paul Barjon 300-1
Austin Cook 300-1
Rafa Cabrera Bello 350-1
Roger Sloan 350-1
Brandon Hagy 350-1
Harry Higgs 350-1
Brian Stuard 350-1
Kevin Tway 400-1
Ben Kohles 400-1
Garrick Higgo 400-1
Henrik Norlander 400-1
Jonathan Byrd 400-1
Scott Gutschewski 400-1
Cole Hammer 400-1
Bill Haas 400-1
Kiradech Aphibarnrat 400-1
Ryan Brehm 500-1
Jim Herman 500-1
Dylan Wu 500-1
Aaron Baddeley 500-1
Richy Werenski 500-1
Curtis Thompson 500-1
Bo Hoag 500-1
Jim Knous 500-1
Seth Reeves 500-1
Wesley Bryan 500-1
Jared Wolfe 500-1
Max McGreevy 500-1
Chris Stroud 500-1
William McGirt 500-1
Jason Dufner 500-1
Camilo Villegas 500-1
Luke Donald 500-1
David Skinns 500-1
Martin Trainer 750-1
Dawie van der Walt 750-1
Andrew Landry 750-1
Sung Kang 750-1
Tommy Gainey 1000-1
Brett Drewitt 1000-1
Brian Gay 1000-1
Joshua Creel 1500-1
Nick Watney 1500-1
Bo Van Pelt 1500-1
Trent Phillips 2500-1
Tommy Gibson 2500-1
Davis Love III 2500-1
Ricky Barnes 2500-1