The Panthers have lost three of their past four home openers, but they had won five in a row prior to that. This is the first time since 2019 they will open their home slate against a team from the NFC and first time in 11 years they will play their first home game against a division opponent, as they defeated the Saints, 35-27, in 2012.
In that 2012 game, each starting quarterback accounted for more than 300 yards of offense. Drew Brees passed for 325 yards with a touchdown and two interceptions, while Cam Newton passed for 253 yards with a TD and no INTs and had 71 yards rushing with another score.
SAINTS vs. PANTHERS SERIES
All-time: The Saints lead the overall series, 29-28, dating back to the first game on Oct. 22, 1995, which was won by the Panthers, 20-3. However, in the regular series, each team has won 28 times. New Orleans won the only playoff meeting, 31-26, in a wild-card game following the 2017 season.