The 66-year-old actress wore a long-sleeved tan sweater along with distressed skinny blue jeans while leaving a Maxfield boutique store.
Melanie completed her outfit with brown shoes and accessorized with earrings and black sunglasses.
The Working Girl star had her short blonde hair parted on the side and added a pop of color with red lipstick.
Melanie carried a pair of black shopping bags as well as a brown purse.
Casual style: Melanie Griffith stepped out in casual style on Monday while shopping in Los Angeles
Earlier this year, Melanie completed the process of the removal of her infamous tattoo tribute to her ex-husband Antonio Banderas, 63.
She began the tattoo removal process back in 2014 after the couple split following 18 years of marriage.
The tattoo was on her bicep and featured Antonio’s first name in a big heart with curly-cue designs around it.
The Lolita actress got the tattoo in the late 90s after she married the Spanish actor.
Melanie replaced the tribute to Antonio with the names of her kids, Alexander Bauer, 38, Dakota Johnson, 34, and Stella Banderas, 27, as well as her stepson, Jesse Johnson, 40.
Antonio was Melanie’s third husband and fourth marriage. They were married in 1996 and divorced in 2015.
She was also married to Scarface actor Steven Bauer, 66, from 1981 to 1989.
Melanie married and divorced Miami Vice actor Don Johnson, 73, twice. Don and Melanie have daughter Dakota together and she has continued the acting tradition in the family.
Shopping session: The 66-year-old actress wore a long-sleeved tan sweater along with distressed skinny blue jeans while leaving a Maxfield boutique store
Tribute tattoo: Earlier this year, Melanie completed the process of the removal of her infamous tattoo tribute to her ex-husband Antonio Banderas, shown in October 2012 in Los Angeles
Famous family: Melanie’s daughter Dakota, shown last week in New York City, has continued the acting tradition in the family
Melanie was born in Manhattan, New York City, to actress Tippi Hendren, 93, and former child stage actor Peter Griffith, who died in 2001 at age 67.
Tippi became an actress after famed director Alfred Hitchcock discovered her after seeing her in a 19761 commercial for a diet drink called Sego.
She made her screen debut playing the leading role in the 1963 Hitchcock film The Birds.
Melanie made her first on-screen appearance as an extra in the 1969 Western movie Smith! and also was an extra in the 1973 film The Harrad Experiment.
She was age 14 when she met Don, then 22, on the set of The Harrad Experiment and they began dating. They had a six-month marriage in 1976, but reconnected and remarried in 1989.