March Madness continues into the last weekend in March with the Sweet Sixteen and Elite Eight. The match-ups and betting lines are set along with updated odds to win the 2023 NCAA Tournament.

Opening round college basketball games saw record March Madness wagering by tens of millions of fans. A majority of them saw their brackets get busted when No. 1 Purdue and No. 2 Arizona lost in major upsets in the opening round. Then No. 1 Kansas was next to fall in the Round of 32 along with No. 2 Marquette.

No. 16 seed Fairleigh Dickinson was the biggest point spread upset in NCAA Tournament history since the field expanded to 64 teams in 1985, and just the second No. 16 seed to every knock off No. 1. While FDU was game in their Round of 32 defeat to Florida Atlantic, it’s now No. 15 Princeton in the South Region as the Cinderella story. The Tigers from the Ivy League are just the fourth No. 15 seed to every advance to the Sweet Sixteen after taking down No. 2 Arizona and No. 7 Missouri.

No. 9 Florida Atlantic in the East Region and No. 9 Arkansas in the West Region join Princeton in the Sweet Sixteen. And so does the only Big Ten team remaining in No. 7 Michigan State after the Spartans took out No. 2 Marquette.

The non-power programs are making their mark in the 2023 NCAA Tournament with five teams into the Sweet Sixteen.

Adjusted Odds to Win 2023 NCAA Tournament

Basketball odds and futures refresh periodically and are subject to change. That includes on props and live betting, which is most popular during March Madness.

• +300: Alabama
• +400: Houston
• +800: Connecticut
• +950: UCLA
• +1000: Gonzaga, Creighton, Texas
• +1500: Tennessee
• +2500: Michigan State
• +2900: Kansas State
• +3000: Xavier
• +3900: San Diego State, Arkansas
• +4800: Florida Atlantic
• +5500: Miami
• +20000 Princeton (SuperBook)

Houston and Alabama are the most popular picks and bets by money (handle) to win the NCAA Tournament followed by UCLA, Texas and Gonzaga at most leading online sportsbooks.

The Four Regional cities hosting Sweet Sixteen and Elite Eight games March 23-26 include:

• Louisville, KY (South) – KFC Yum! Center
• New York, NY (East) – Madison Square Garden
• Kansas City, MO (Midwest) – T-Mobile Center
• Las Vegas, NV (West) – T-Mobile Arena

Las Vegas hosts an NCAA Tournament game for the first time after gambling on games was not acceptable by the NCAA until PASPA was overturned in 2018. Now, more than 30 states have legal sports betting and a record 68 million American’s wagering on the the most popular sporting event of the year continues.

The Final Four will be April 1 and 3 at NRG Stadium in Houston, TX.

NCAA Tournament – Updated Bracket, Schedules and Scores

Sweet 16 Matchups, Odds, TV Schedule

Betting lines, odds and over/under game totals by region courtesy of FanDuel Sportsbook. All times Eastern.

Thursday, March 23

• No. 3 Kansas State vs. No. 7 Michigan State (-1.5) | Total: 136.5 | 6:30 p.m. | TBS (New York)
• No. 9 Arkansas vs. No. 3 Connecticut (-3.5) | Total: 139.5 | 7:15 p.m. | CBS (Las Vegas)
• No. 9 Florida Atlantic vs. No. 4 Tennessee (-5.5) | Total: 131.5 | 9:00 p.m. | TBS (New York)
• No. 3 Gonzaga vs. No. 2 UCLA (-1.5) | Total: 145.5 | 9:45 p.m. | CBS (Las Vegas)

Friday, March 24 (Sweet 16)

• No. 5 San Diego State vs. No. 1 Alabama (-6.5) | Total: 134.5 | 6:30 p.m. | TBS (Louisville)
• No. 5 Miami vs. No. 1 Houston (-6.5) | Total: 138.5 | 7:15 p.m. | CBS (Kansas City)
• No. 15 Princeton vs. No. 6 Creighton (-10) | Total: 140 | 9:00 p.m. | TBS (Louisville) *SuperBook odds
• No. 3 Xavier vs. No. 2 Texas (-4.5) | Total: 148.5 | 9:45 p.m. | CBS (Kansas City)

More NCAA Tournament game analysis, predictions and picks with information you can bet on at The Duel Sports.

Saturday, March 25 (Elite 8)

Sunday, March 26 (Elite 8)

• TBD vs TBD | 2 p.m. | CBS
• TBD vs TBD | 4:55 p.m. | CBS

NCAA Tournament facts and betting figures from the opening rounds betting market March 16-19.

Thursday NCAA favorites went 11-5 straight up (SU) and 8-8 against the spread (ATS) with five outright underdog winners. Totals (Over/Under) went 6-10 with all records from closing lines and Vegas Stats & Information (VSIN) updates.

Friday favorites went 13-3 SU and 10-6 ATS. Totals were dominated by unders going 14-2. So opening round NCAA Tournament action betting was 24-8 SU & 18-14 ATS (56.3% ATS) for favorites. Totals were 8-24 over/under with less scoring than expected.

Saturday’s Round of 32 saw favorites go 5-3 SU and 3-4-1 ATS. Totals were 2-6 over/under.

Sunday’s Round of 32 had favorites at 4-4 SU and 2-6 ATS. Totals were 6-2 over/under.

This late foul by TCU with less than one second left allowed Gonzaga (-4.5) to sink a pair of free throws to go up by 6-points. Then the amazing last second TCU shot to give Horned Frogs better delight.

So far through the NCAA Tournament, including the First Four games, betting favorites are 35-17 and 26-25-1 ATS. Unders are still the most profitable in totals betting with a mark of 17-35, or 17 overs and 35 unders.

If you’re still betting futures and odds of teams to win the NCAA Tournament, here is another stat profile from VSIN – 19 of the last 20 National Champions have finished in the Top 20 in Ken Pom’s offensive and defensive adjusted efficiency rankings.

Houston, UCLA, Alabama, UConn and Texas fit that profile with Creighton just missing. You’re 2023 NCAA Tournament and national champion is most likely in that group.

You can bet on it.